91探花

Jonathan Young

Jonathan Young, portrait
Post-Doctoral Researcher
Molecular Cellular Biology
youngj8@ohio.edu

Department of Biomedical Sciences/Edison Biotechnology Institute, Heritage College of Osteopathic Medicine

Education

Degrees Earned: Doctor of Philosophy, December 2018.
Field of Study: Molecular and Cellular Biology, Department of Biological Sciences
Certificate in Bioinformatics
91探花, Athens, Ohio
Adviser: John J. Kopchick, Ph.D.

Bachelor of Science, June 2012
Major: Microbiology
Minor: Chemistry
91探花, Athens, Ohio

Research

Growth hormone (GH) has diverse metabolic functions in addition to promoting growth. My research involves the relationship between GH and adipose tissue as well as GH and the intestine. The adipose portion of my research is focused on GH鈥檚 effects on the transcriptome of subcutaneous and visceral adipose depots across species and throughout the spectrum of GH action. The intestinal portion of my research centers around the effects of GH alterations on the gut microbiome and gut morphology.

Selected Publications

Young, J. A., Henry, B. E., Benencia, F., Bell, S., List, E. O., Kopchick, J. J., & Berryman, D. E. (2020). GHR 鈭/鈭 Mice are protected from obesity鈥恟elated white adipose tissue inflammation. Journal of Neuroendocrinology.

Young, J. A., Jensen, E. A., Stevens, A., Duran-Ortiz, S., List, E. O., Berryman, D. E., & Kopchick, J. J. (2019). Characterization of an intestine-specific GH receptor knockout (IntGHRKO)mouse. Growth Hormone and IGF Research, 46鈥47, 5鈥15.

Young, J. A., List, E. O., & Kopchick, J. J. (2016). Deconstructing the Growth Hormone Receptor(GHR): Physical and Metabolic Phenotypes of Tissue-Specific GHR Gene-Disrupted Mice. In F. F. Casanueva (Ed.), Progress in Molecular Biology and Translational Science (Vol. 138, pp. 27鈥39). Academic Press.

Duran鈥怬rtiz, S., Young, J. A., Jara, A., Jensen, E. A., Basu, R., List, E. O., Qian, Y., Kopchick, J. J., & Berryman, D. E. (2020). Differential gene signature in adipose tissue depots of growth hormone transgenic mice. Journal of Neuroendocrinology.

Jensen, E. A., Young, J. A., Jackson, Z., Busken, J., List, E. O., Carroll, R. K., Kopchick, J. J., Murphy, E. R., & Berryman, D. E. (2020). Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice. Endocrinology, 161(4).

Soendergaard, C., Young, J., & Kopchick, J. (2017). Growth Hormone Resistance鈥擲pecial Focus on Inflammatory Bowel Disease. International Journal of Molecular Sciences, 18(5), 1019.

Troike, K. M., Henry, B. E., Jensen, E. A., Young, J. A., List, E. O., Kopchick, J. J., & Berryman, D. E. (2017). Impact of Growth Hormone on Regulation of Adipose Tissue. In Comprehensive Physiology (Vol. 7, Issue 3, pp. 819鈥840). John Wiley & Sons, Inc.